Cost-effectiveness analysis of esophageal cancer once-in-a-lifetime endoscopic screening in high-risk areas of rural China / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 476-480, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-286796
ABSTRACT
<p><b>OBJECTIVE</b>To estimate the cost-effectiveness of esophageal cancer endoscopic screening once-in-a-lifetime and to predict the optimal screening age for people in high-risk areas of rural China.</p><p><b>METHODS</b>A Markov model was constructed to predict and compare the effect of four esophageal cancer endoscopic screening modalities which varied with different screening ages. Long-term epidemiological effectiveness and cost-effectiveness were predicted by simulation of the model.</p><p><b>RESULTS</b>Compared with the control group, strategies starting at 40, 45, 50 and 55 year-old had saved life-years of 629.51, 769.88, 738.98 and 533.21 years per 100 000 people, respectively, of which the strategy starting at 45 year-old saved the maximum life years. All strategies were cost-effective and starting at 40 year-old cost the most per life-year saved. Among all alternatives, strategies starting age at 45 year-old and 50 year-old were incremental cost-effective, and the incremental cost-effective ratios were 34 962.87 and 3 346.43 RMB per life year saved, respectively.</p><p><b>CONCLUSIONS</b>The strategy starting at 40 year-old implemented at present and other strategies were cost-effective in high-risk areas of rural China. However, the 45-year-old group is more aligned with the principle of cost-effectiveness. Considering the cost-effectiveness of different strategies and social economic status, 45 year-old is regarded as the optimal starting age of esophageal cancer once-in-a-lifetime endoscopic screening and is recommended in areas lacking health resources. The strategy of starting age at 40 year-old which could obtain better screening effects would be preferable in wealthy regions.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Población Rural
/
Neoplasias Esofágicas
/
Estudios de Casos y Controles
/
China
/
Cadenas de Markov
/
Factores de Edad
/
Esofagoscopía
/
Análisis Costo-Beneficio
/
Diagnóstico
/
Economía
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Evaluación Económica en Salud
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Adulto
/
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Oncology
Año:
2015
Tipo del documento:
Artículo
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