Effect of gamma-aminobutyric acid on the sperm acrosin activity / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVES</b>To investigate the effect of gamma-aminobutyric acid (GABA) on the sperm acrosin activity in normal men and positive antisperm antibody (AsAb) men.</p><p><b>METHODS</b>Sperm acrosin activity was detected by BAEE/ADH method.</p><p><b>RESULTS</b>GABA could increase the sperm acrosin activity in normal and AsAb positive patients (P < 0.01). The results also indicated that GABA significantly increased Na(+)-K(+)-ATPase activity (P < 0.01), Ca(2+)-ATPase activity (P < 0.05) and SOD activity (P < 0.01) of sperm.</p><p><b>CONCLUSIONS</b>The results demonstrated that GABA could influence the sperm acrosin activity.</p>