Treatment and prognosis of anaplastic thyroid carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1493-1497, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-288562
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the treatment model and the factors that influence survival of the patients with anaplastic thyroid carcinoma (ATC).</p><p><b>METHODS</b>The clinical data of all patients with ATC in our hospital from May. 1970 to May. 2005 were analyzed retrospectively with regard to mortality and survival rate (Kaplan-Meier). Multivariate analysis was performed by the Cox proportional hazard model.</p><p><b>RESULTS</b>Fifty cases together were analyzed. The overall 1-year, 3-year, 5-year survival rate were 39.4%, 29.6% and 20.7% respectively. The median survival time was 6 months. Univariate analysis showed the patients with their age < 55 years old, without distant metastasis, white blood cell count < 10.0 x 10(9)/L at presentation, without receiving chemotherapy, receiving radiotherapy with the dose no less than 40 Gy, receiving multiple modality therapy had a better prognosis. White blood cell count at presentation, the model of therapy were the risk factors independently influencing prognosis by multivariate analysis.</p><p><b>CONCLUSIONS</b>White blood cell count at presentation, receiving surgery and postoperative radiotherapy or not were the risk factors independently influencing prognosis. The prognosis of anaplastic thyroid carcinoma was worse; the patients with ATC maybe get a better prognosis by receiving surgery and postoperative radiotherapy.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Terapéutica
/
Neoplasias de la Tiroides
/
Carcinoma
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Resultado del Tratamiento
/
Diagnóstico
/
Estimación de Kaplan-Meier
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Surgery
Año:
2006
Tipo del documento:
Artículo
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