Relationship between prognosis of nasal inverted papilloma and human papillomavirus types / 中华耳鼻咽喉头颈外科杂志
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
;
(12): 195-198, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-288917
ABSTRACT
<p><b>OBJECTIVE</b>To detected HPV human papillomavirus DNA and HPV types in NIP nasal inverted papilloma, to inquire into the infection of HPV in the pathogenesis of NIP, and the relationship of HPV with the prognosis of NIP.</p><p><b>METHODS</b>Twenty-eight cases of NIP were divided into 3 groups no recurrence group (group 1), recurrence group (group 2), squamous cell carcinoma (SCC) arising in NIP group (malignancy group, group 3). Ten cases of benign nasal polyps were used as control group. HPV-DNA types of 6, 11, 16, 18 and general type were detected by polymerase chain reaction (PCR).</p><p><b>RESULTS</b>Total positive rate of HPV in NIP was 75% (21/28). The positive rate of group 1 was 42% (5/12), all with single and low risk HPV type infection (4 with HPV6 and 1 with HPV11). Thirteen cases of recurrence and 3 cases of malignancy were discovered to have HPV-DNA, in group 2, the majority were HPV6 and HPV11, 4 cases with double infection;in group 3, the majority were HPV16 and HPV18, and 2 cases with double infection.</p><p><b>CONCLUSIONS</b>The occurrence of NIP was related with HPV infection. To detected HPV and its subtypes can show the cases easily to have recurrence or malignant change. For the cases with HPV positive, double infection and infected with high risk types should be closely followed-up.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Papillomaviridae
/
Pronóstico
/
Virología
/
Neoplasias de los Senos Paranasales
/
Estudios de Casos y Controles
/
Neoplasias Nasales
/
Clasificación
/
Papiloma Invertido
/
Infecciones por Papillomavirus
/
Diagnóstico
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Año:
2005
Tipo del documento:
Artículo
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