An experimental investigation of deep burn by constant low heat / 中华烧伤杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the basic pathogenetic rule and mechanism of deep burn by constant low heat.</p><p><b>METHODS</b>Animal burn model inflicted by constant low heat was established as follows. (1) The rats were randomly divided into groups in terms of temperature and duration of contact. The burn wound formation process, the skin tissue density and pathomorphological changes in the rats were observed after burn was produced on the back by contacting heat source constantly. (2) The subcutaneous temperature of the back was monitored at different time and temperatures of heat contacting by placing the thermometer under the fascia of the rat back.</p><p><b>RESULTS</b>(1) The time of burn wound formation was shortened and the injury degree deepened along with the increase in the contact temperature. The rat skin density exhibited irregular hyperbola or triple curves. (2) The subcutaneous temperature exhibited a parabolic curve with fixed experimental conditions.</p><p><b>CONCLUSION</b>(1) The sharp increase in subcutaneous temperature leading to degeneration and necrosis might be the primary cause of deep burn. (2) The regularity of the skin tissue injury was the result of multiple effects of heat-origin injury, increase of capillary permeability and the change in tissue mass.</p>