Aeromonas Sobria Infection in Patients with Acute Leukemia:Clinical Features and Outcome / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 711-714, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-289922
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical features and outcome of patients with acute leukemia and Aeromonas sobria infection.</p><p><b>METHODS</b>The clinical data of two patients from Peking Union Medical College Hospital from 1994 to 2014 as well as patients reported in English literature (from PubMed and Medline databases) and Chinese literature (China Hospital Knowledge Database) during the same period were retrospectively analysed. Data were extracted and analyzed using Chi-square tests.</p><p><b>RESULTS</b>Totally 15 patients worldwide were available for analysis with a male-to-female ratio of 123 and an acute myeloid leukemia to acute lymphoblastic leukemia ratio of 105. The median age was 49.5 years (range27-80 years). Most patients were neutropenic at the time of onset of fever,and the most common manifestation was lower limb infection (66.7%). Despite empirical antibiotics treatment,the mortality was still as high as 80%. Chi-square tests revealed that among the dead patients,the rates of lower limb infection (P<0.01) and septic shock (P=0.02) were significantly higher.</p><p><b>CONCLUSION</b>Aeromonas sobria infection is an uncommon but highly fatal condition that requires special attention in clinical settings.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Leucemia Mieloide Aguda
/
Estudios Retrospectivos
/
Resultado del Tratamiento
/
Infecciones por Bacterias Gramnegativas
/
Aeromonas
/
Beijing
Tipo de estudio:
Estudio observacional
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2015
Tipo del documento:
Artículo
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