RNA Interference in Functional Genomics and Medicine
Journal of Korean Medical Science
;
: 309-318, 2003.
Artículo
en Inglés
| WPRIM
| ID: wpr-29063
ABSTRACT
RNA interference (RNAi) is the sequence-specific gene silencing induced by double-stranded RNA (dsRNA). Being a highly specific and efficient knockdown technique, RNAi not only provides a powerful tool for functional genomics but also holds a promise for gene therapy. The key player in RNAi is small RNA (~22-nt) termed siRNA. Small RNAs are involved not only in RNAi but also in basic cellular processes, such as developmental control and heterochromatin formation. The interesting biology as well as the remarkable technical value has been drawing widespread attention to this exciting new field.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Terapia Genética
/
Genómica
/
Interferencia de ARN
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2003
Tipo del documento:
Artículo
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