Effects of recombined neuregulin on healthy Macaca mulatta hearts / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 154-156, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-291277
ABSTRACT
To explore the effects of recombined Neuregulin on the heart of healthy Macaca mulatta, 10 healthy adult Macaca mulatta were randomly divided into two groups and were injected with the same doses of recombined Neuregulin and normal saline, respectively. At the same time, related indices were detected by 2-dimensional echocardiography and M-mode echocardiography. All indices were compared between the two groups and among different phases. Recombined Neuregulin had effects on LVEDD (left ventricular end-diastolic diameter), LVEDV (left ventricular end-diastolic volume), LVESV (left ventricular end-systolic volume) and SV (Stroke volume), and the effects changed with time. However, no significant changes were seen on EF (Ejection fraction) and FS (Fractional shortening). In conclusion, recombined Neuregulin has effects on the left ventricular volume of healthy Macaca mulatta, but no significant effect on cardiac contractility.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Volumen Sistólico
/
Proteínas Recombinantes
/
Diagnóstico por Imagen
/
Ecocardiografía
/
Distribución Aleatoria
/
Neurregulinas
/
Genética
/
Ventrículos Cardíacos
/
Macaca mulatta
Tipo de estudio:
Estudio diagnóstico
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2008
Tipo del documento:
Artículo
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