Your browser doesn't support javascript.
loading
Cell origin of localized Castleman's disease of hyaline-vascular type / 中华血液学杂志
Chinese Journal of Hematology ; (12): 397-400, 2004.
Artículo en Chino | WPRIM | ID: wpr-291408
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the cell features of 6 Castleman's disease patients and evaluate their prognosis.</p><p><b>METHODS</b>The resected tumors were investigated by routine histopathology and immunohistochemistry. Reverse-transcript PCR (RT-PCR) and sequencing of RT-PCR products were used to assess the clonal characters of the main tumor cells.</p><p><b>RESULTS</b>Histologically, all of the 6 tumors were classified as the hyaline vascular type. B-cells dominated the follicular germinal centers, with T-cells dispersing inter-follicularly. The results of RT-PCR each obtained a single band of either 128 bp or 122 bp and sequencing showed that there was highly homogeneity within the same length sequences, accompanied by fewer different nucleotide acids.</p><p><b>CONCLUSION</b>Monoclonal and/or oligoclonal B cells were identified in Castleman's disease. These B cells were originated from germinal center cells.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Pronóstico / Inmunohistoquímica / Linfocitos B / Reordenamiento Génico de Cadena Pesada de Linfocito B / Enfermedad de Castleman / Células Clonales / Antígenos Comunes de Leucocito / Antígenos CD20 / Reacción en Cadena de la Polimerasa de Transcriptasa Inversa Tipo de estudio: Estudio pronóstico Límite: Adolescente / Adulto / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Hematology Año: 2004 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Pronóstico / Inmunohistoquímica / Linfocitos B / Reordenamiento Génico de Cadena Pesada de Linfocito B / Enfermedad de Castleman / Células Clonales / Antígenos Comunes de Leucocito / Antígenos CD20 / Reacción en Cadena de la Polimerasa de Transcriptasa Inversa Tipo de estudio: Estudio pronóstico Límite: Adolescente / Adulto / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Hematology Año: 2004 Tipo del documento: Artículo