Advances in the researches of lutein and alzheimer's disease / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 456-460, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-291619
ABSTRACT
Lutein, a kind of oxycarotenoid, can pass the blood brain barrier and preferentially accumulate in the human brain, which is the most abundant carotenoid in human brain. Evidence from multiple studies suggested that lutein was closely related to age-related cognitive decline and risk of Alzheimer's disease (AD) in human. Dietary, plasma and brain concentrations of lutein were negatively associated with age-related cognitive decline. Lutein concentrations in plasma and brain were significantly lower in AD patients than those of health control. In human brain, lutein was the sole carotenoid which consistently associated with a range of cognitive function measures. In elderly women, lutein supplement can improve the cognitive function. In this article, we systematically reviewed the literature on the role of lutein in age-related cognitive decline and alzheimer's disease and its possible mechanisms. It may prove some benefit information for the advanced research and prevention of AD.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Luteína
/
Encéfalo
/
Carotenoides
/
Cognición
/
Suplementos Dietéticos
/
Dieta
/
Enfermedad de Alzheimer
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Preventive Medicine
Año:
2015
Tipo del documento:
Artículo
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