Research progress on seroepidemiological study of enterovirus 71 and coxsackievirus A16 infection among children / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 184-188, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-291654
ABSTRACT
Most common causative agents for hand, foot and mouth disease (HFMD) are enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16). The symptomatic and asymptomatic cases could transmit the disease in population. Many sero-epidemiological surveys were launched to estimate the sero-incidence of EV-A71 and CV-A16 enterovirus, the susceptibility of different sub-population, and to observe the dynamics of neutralizing antibody. A literature search of sero-epidemiological study focused on EV-A71 or CV-A16 was conducted via PubMed and China Hospital Knowledge Database. Based on the 20 selected studies, the different age groups' antibody level, the susceptibility, the dynamics of antibody and sero-incidence of EV-A71 or CV-A16 were analyzed. From our results, the antibody level against EV-A71 or CV-A16 in neonates was associated with their mothers, which was similar with that of adults. The antibody level against EV-A71 or CV-A16 in neonates dropped to lowest level at one years-old, and started to dramatically increase until four years-old, and reached a plateau at five years-old. In conclusion, the infants aged 6-12 months were the priority group to receive vaccination when the EV-A71 vaccine is licensed in the future.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Estudios Seroepidemiológicos
/
China
/
Factores de Edad
/
Vacunación
/
Enterovirus
/
Enterovirus Humano A
/
Anticuerpos Neutralizantes
/
Inmunidad Adaptativa
/
Inmunidad Materno-Adquirida
/
Madres
Límite:
Adulto
/
Niño
/
Humanos
/
Lactante
/
Recién Nacido
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Preventive Medicine
Año:
2015
Tipo del documento:
Artículo
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