A comparative study of the effects of Acanthopanacis senticosi injection, theophylline and caffeine on human sperm mobility in vitro / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To compare the effect of Acanthopanacis senticosi injection, theophylline and caffeine on human sperm mobility in vitro.</p><p><b>METHODS</b>We incubated the sperm aseptically obtained by masturbation from 12 asthenospermia men and treated by swim-up technique in Acanthopanacis senticosi injection (10 g/L), theophylline (3 mmol/L) and caffeine (7 mmol/L) respectively, and detected various sperm parameters with the computer-assisted sperm analysis (CASA) system at 0 h, 1 h and 3 h.</p><p><b>RESULTS</b>Acanthopanacis senticosi injection significantly increased sperm motility, the percentage of progressive motile sperm, straight line velocity (VSL) and curvilinear velocity (VCL) as compared with theophylline and caffeine (P < 0.05).</p><p><b>CONCLUSION</b>Acanthopanacis senticosi injection can activate the mobility of human sperm in vitro.</p>