Studies on metabolites from marine microorganism Aspergillus terreus collected from nature reserve region of mangrove / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To search for new antitumor active lead compounds from marine microorganism.</p><p><b>METHOD</b>A marine strain, Aspergillus terreus, was cultured and up-scaled in artificial seawater media, from which the metabolites were isolated and elucidated by using modern spectroscopy techniques.</p><p><b>RESULT</b>Twelve compounds were isolated from mycelia and fermentation broth of A. terreus.</p><p><b>CONCLUSION</b>Compounds 1-4 were steroids, compounds 5-8 were organic acids and esters, compound 9 was an alkaloid, compound 10 was an isocoumarin, compound 11 was ceramide, compound 12 was propenyl cyclic pentanediol.</p>