Effect of danshensu, protocatechualdehyde and danshen injection on calcium ion concentration in cytoplasm of human erythrocytes / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 984-988, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-293655
ABSTRACT
<p><b>OBJECTIVE</b>To study the predominant calcium-antagonist components of Danshen injection.</p><p><b>METHOD</b>The effects of danshensu, protocatechualdehyde and Danshen injection on calcium concentration in cytoplasm of erythrocytes were examined in vitro by the fluorescent Ca+ -chelator fura-2.</p><p><b>RESULT</b>Either DS182 or PCAD can decrease in dose-dependent cytosolic free calcium concentration in human erythrocytes. They had additive effect when mixed, which was similar to Danshen injection.</p><p><b>CONCLUSION</b>DS182 and PCAD may be predominant calcium-antagonist components of Danshen injection.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Plantas Medicinales
/
Benzaldehídos
/
Medicamentos Herbarios Chinos
/
Catecoles
/
Química
/
Calcio
/
Salvia miltiorrhiza
/
Citoplasma
/
Sinergismo Farmacológico
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2004
Tipo del documento:
Artículo
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