Study on the effects of two kinds of cactus polysaccharide on erythrocyte membrane protein and fluidity of the lipid in S180 mice / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the effects of two kinds of cactus polysaccharide on Band 3 protein, cross-linking protein and lipid fluidity of erythrocyte membrane in S180 mice.</p><p><b>METHOD</b>The membrane protein content was analysed by SDS-PAGE. Lipid fluidity was measured by Skinitzky method.</p><p><b>RESULT</b>The two kinds of cactus polysaccharide increased the content of Band 3 protein and decreased the content of cross-linking protein, raised the lipid fluidity. While the effect of median dose group of medical cactus polysaccharide is very remarkable (P < 0.01), the effect of high dose group of edible cactus polysaccharide is very remarkable (P < 0.01).</p><p><b>CONCLUSION</b>By improving the erythrocyte membrane function of tumor-mice, they enhanced the immune function, which may be one of anti-tumor mechanisms.</p>