Research on components of Cornus officinalis extracted by supercritical carbon dioxide / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of Cornus officinalis extracted by supercritical carbon dioxide fluid extraction (SFE).</p><p><b>METHOD</b>The process was performed at 40 centigrade with pressures of 15 MPa for 2 hours and with CO2 fluid and gas at the flow rate of 22.0 kg x h(-1) and 18.0 kg x h(-1) respectively. The chemical constituents of the SFE extractions were determined by GC-MS.</p><p><b>RESULT</b>The total amount of extractable substances or yields by SFE is 2.42% (mass). 31 Chemical constituents were identified and their relative contents were determined by normalization method of area.</p><p><b>CONCLUSION</b>The major components identified in the extractions are 1,2-benzenedicarboxylic acid, butyl 2-methylpropyl ester, isopropyl myristate etc.</p>