Application of ultraviolet spectroscopy for rapid analysis in extraction process of danhong injection / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1676-1678, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-294044
ABSTRACT
In this work, a rapid analysis method basing on ultraviolet spectroscopy was established for the determination of danshensu, protocatechuic aldehyde, rosmarinci acid, lithospermic acid and salvianolic acid B in the extraction process of Danhong injection. In the extraction process of Danshen and Honghua crude drugs, 44 extraction solution samples were collected and the contents of the five components were determined by HPLC analysis. The ultraviolet spectra of the samples were collected. Partial least square regression was used to establish the multivariate calibration models between the ultraviolet spectra and the contents of the five components. The results showed that the established models could predict the contents of the five components in the extraction solution accurately. The ultraviolet spectroscopy method established in this work can be used for rapid analysis of the intermediates of Danhong injection, which may be applied for the quality control in the manufacturing process.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Control de Calidad
/
Estándares de Referencia
/
Espectrofotometría Ultravioleta
/
Medicamentos Herbarios Chinos
/
Química
/
Química Farmacéutica
/
Cromatografía Líquida de Alta Presión
/
Salvia miltiorrhiza
/
Métodos
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2013
Tipo del documento:
Artículo
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