Mitochondrial genetics and human essential hypertension / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 293-295, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-295491
ABSTRACT
Mitochondrial DNA (mtDNA) exhibits matrilineal inherence. Familial mitochondrial diseases caused by mtDNA mutations are generally involved in organs featuring high energy consumption, which include heart, brain and skeletal muscle. Recently, it has been found that some essential hypertension patients featured classical maternal inheritance, which has confirmed and enriched mtDNA mutations as one of the molecular mechanisms underlying maternally inherited hypertension. Nevertheless, more general as well as radical questions are still to be answered. This article reviews recent advance in mitochondrial genome evolution, mtDNA genetics and the role of mtDNA mutations in maternally inherited hypertension.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
ADN Mitocondrial
/
Evolución Molecular
/
Genética
/
Hipertensión
/
Mitocondrias
/
Mutación
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2012
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS