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Molecular epidemiological study on prevalence of human papillomaviruses in patients with common warts in Beijing area / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences ; (12): 55-61, 2009.
Artículo en Inglés | WPRIM | ID: wpr-296003
ABSTRACT
<p><b>OBJECTIVE</b>To study the circulation, distribution, and genomic diversity of HPVs in common warts in Beijing area of China.</p><p><b>METHODS</b>Forty eight patients with pathologically diagnosed common warts were screened for the presence of HPV with HPV type-specific PCR and direct sequencing analysis. The genomic diversity of HPVs prevalent in Chinese patients was analyzed based on LCR.</p><p><b>RESULTS</b>Forty one (85.5%) samples were positive for HPV DNA, 13 (31.7%)--HPV-57, 12 (29.3%)--HPV-1a, 7 (17%)--HPV-27 and 5(12.2%)--HPV-2a. Four cases were infected with two different HPV types, two (4.9%) with HPV-1a and HPV-27, one (2.4%) with HPV-1 and HPV-57 and one (2.4%) with HPV-27 and HPV-57. In contrast to the prevalence of single strain of novel HPV-57 variant and HPV-1 prototype, two HPV-2 and three HPV-27 novel variants were found to circulate in Beijing.</p><p><b>CONCLUSION</b>HPV-1, -2, -27 and -57 are predominantly prevalent in patients with common warts in Beijing.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Papillomaviridae / Filogenia / Variación Genética / Virología / ADN Viral / Verrugas / China / Epidemiología / Prevalencia / Clasificación Tipo de estudio: Estudio de prevalencia Límite: Adolescente / Adulto / Anciano / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Biomedical and Environmental Sciences Año: 2009 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Papillomaviridae / Filogenia / Variación Genética / Virología / ADN Viral / Verrugas / China / Epidemiología / Prevalencia / Clasificación Tipo de estudio: Estudio de prevalencia Límite: Adolescente / Adulto / Anciano / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Biomedical and Environmental Sciences Año: 2009 Tipo del documento: Artículo