Research Progress in Mechanisms Associated with Latent Infection in Humans by the Cytomegalovirus / 病毒学报
Chinese Journal of Virology
;
(6): 82-87, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-296213
ABSTRACT
The human cytomegalovirus (HCMV) is a widespread herpesvirus. Virus reactivation from latency can lead to stillbirth, miscarriage, fetal anomalies, and intrauterine growth retardation. During latent infection with the HCMV, the virus can be cleared by the immune response or apoptosis of host cells. However, the HCMV has developed several strategies to manipulate expression of its genes and the microenvironment of host cells. Recent studies have shown that latent infection with the HCMV is associated with viral regulation of early expression of genes; evasion of cell death; evasion of the immune response; regulatin of non-coding RNAs. This review summarizes recent research progress on the mechanisms underpinning latent infection with the HCMV.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Proteínas Virales
/
Virología
/
Latencia del Virus
/
Infecciones por Citomegalovirus
/
Citomegalovirus
/
Alergia e Inmunología
/
Genética
/
Metabolismo
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Virology
Año:
2016
Tipo del documento:
Artículo
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