TMSG-1 and its roles in tumor biology / 癌症
Chinese Journal of Cancer
;
(12): 697-702, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-296367
ABSTRACT
TMSG-1 is a newly discovered tumor metastasis suppressor gene, which plays important roles in promoting apoptosis and inhibiting invasion and metastasis of tumor cells. The inhibitory function of TMSG-1 in tumor cells may be related to vacuolar H+-ATPase and ceramide, but the underlying mechanism remains unknown. Studies on TMSG-1 are limited worldwide, and only a research group in Shanghai and our group have recently studied on it. As a new research field, the function of TMSG-1 remains to be explored. This review discusses the discovery of TMSG-1, structure of its encoded protein, its roles and possible mechanism in inhibiting tumor invasion and metastasis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Farmacología
/
Fosforilación
/
Fisiología
/
Ciclo Celular
/
Ceramidas
/
Apoptosis
/
ATPasas de Translocación de Protón Vacuolares
/
Proteínas Supresoras de Tumor
/
Activación Enzimática
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Chinese Journal of Cancer
Año:
2010
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS