Correlation analysis of efficacy of yiqi chutan recipe in treating NSCLC and P4HB expression / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 184-187, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-297457
ABSTRACT
<p><b>OBJECTIVE</b>To study the predicting effect of proly 4-hydroxylase beta polypeptide (P4HB) in treating non-small cell lung cancer (NSCLC) patients by Yiqi Chutan Recipe (YCR).</p><p><b>METHODS</b>Totally 46 stage III and IV NSCLC patients were treated by YCR for 4 therapeutic courses. Effect was assessed by RECIST of solid tumor. P4HB expression was detected in the lung cancer tissue by immunohistochemical assay. Factors affecting disease control rates (DCR) of YCR were analyzed by Logistic regression analysis. The correlation between P4HB expression and the effect of YCR was analyzed.</p><p><b>RESULTS</b>The DCR of advanced NSCLC treated by YCR was 36.96% (17/46 cases). P4HB was high expressed in advanced lung cancer tissue (6/15 cases). Gender, initial treatment, and retreatment are independent factors for affecting DCR of treating lung cancer by YCR.</p><p><b>CONCLUSION</b>P4HB might be taken as a factor for predicting the effect of YCR in treating NSCLC.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Medicamentos Herbarios Chinos
/
Carcinoma de Pulmón de Células no Pequeñas
/
Procolágeno-Prolina Dioxigenasa
/
Proteína Disulfuro Isomerasas
/
Usos Terapéuticos
/
Quimioterapia
/
Pulmón
/
Neoplasias Pulmonares
/
Metabolismo
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2015
Tipo del documento:
Artículo
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