Clinicopathologic analysis of 254 cases of papillary thyroid microcarcinoma / 中华病理学杂志
Chinese Journal of Pathology
;
(12): 258-261, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-298123
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the prognostic impact of tumor size, ultrasonography, central neck lymph node involvement, and age of patients in papillary thyroid microcarcinoma (PTMC).</p><p><b>METHODS</b>Two hundred and fifty-four patients who underwent total thyroidectomy and central neck dissection for PTMC between 2012 and 2014 were included in this retrospective study. Statistical correlation between tumor size and various clinicopathological parameters was assessed by univariate and multivariate analyses. The ultrasound findings were also evaluated.</p><p><b>RESULTS</b>A total of 254 patients (199 females and 55 males) were included in this study. PTMC showed a predilection for female patients, 41-50 years of age (43.3% of all cases, 110/254), and ultrasound showed hypoechoic nodules. Statistically significant correlation was demonstrated between central neck lymph node involvement and the following factors age and tumor size. A tumor diameter greater than 0.5 mm (67.3% of all cases) most commonly occurred in patients older than 41 years, and was associated with a higher risk of metastatic central neck lymph node involvement (P<0.05). Hashimoto's thyroiditis was noted in the background in 39.4%(100/254) of cases.</p><p><b>CONCLUSIONS</b>Tumor size appears to have a prognostic impact in PTMC, and larger size is more likely to be associated with a higher risk of central neck lymph node involvement. It is controversial whether the etiology of papillary thyroid carcinoma is related to Hashimoto's thyroiditis.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Pronóstico
/
Disección del Cuello
/
Cirugía General
/
Tiroidectomía
/
Neoplasias de la Tiroides
/
Diagnóstico por Imagen
/
Carcinoma
/
Carcinoma Papilar
/
Estudios Retrospectivos
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Pathology
Año:
2015
Tipo del documento:
Artículo
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