Bioinformatic identification and analysis of Schistosoma japonicum adenine phosphoribosyltransferase / 南方医科大学学报
Journal of Southern Medical University
;
(12): 272-275, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-298189
ABSTRACT
<p><b>OBJECTIVE</b>To identify adenine phosphoribosyltransferases in Schistosoma japonicum and analyze their structural features.</p><p><b>METHODS</b>Based on the accessible transcriptome and proteomic data, the S. japonicum adenine phosphoribosyl transferases were identified using bioinformatics approaches including bi-directional homology comparison, domain search and phylogenetic analysis. Homology modeling was also performed to describe the structural features of the proteins.</p><p><b>RESULTS AND CONCLUSION</b>Two homologue sequences of adenine phosphoribosyltransferase were obtained from S. japonicum, and the EST abundance, physico-chemical properties and three-dimensional structures of them were also acquired.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Filogenia
/
Conformación Proteica
/
Schistosoma japonicum
/
Adenina Fosforribosiltransferasa
/
Modelos Moleculares
/
Proteínas del Helminto
/
Química
/
Biología Computacional
/
Genética
/
Isoenzimas
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Southern Medical University
Año:
2007
Tipo del documento:
Artículo
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