Studies on extraction of Ligusticum chuanxiong in Hongye Xintong soft capsule by super critical fluid extraction / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 161-164, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-298443
ABSTRACT
<p><b>OBJECTIVE</b>To study the rationality of extraction prosess for the Ligusticum chuanxiong in Hongye Xintong Soft Capsule by super critical fluid extraction(SFE).</p><p><b>METHOD</b>Conditions for the extraction were optimized by orthogonal experimental design as guided by the extraction rate and content of ligustilid in the extract; Combined with the experiment of rats ligated the left coronary artery, the two compounds containing different extracts (steam distillation and SFE) were compared to determine the extraction prosess.</p><p><b>RESULT</b>The best extraction conditions were established as following pressure 30 MPa, temperature 50 degrees C, extracting time 4 h, separate pressure 10 MPa. separate temperature 40 degrees C. Compared with steam distillation, the compound containing SFE extract showed stronger protective effects on rats ligated the left coronary artery.</p><p><b>CONCLUSION</b>Super critical fluid can extract active ingredients in Ligusticum chuanxiong effectively.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Presión
/
Temperatura
/
Factores de Tiempo
/
Cápsulas
/
Medicamentos Herbarios Chinos
/
Agua
/
Química
/
Vasos Coronarios
/
Cromatografía con Fluido Supercrítico
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2009
Tipo del documento:
Artículo
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