The Current Status of Directed Differentiation Technology / 한양의대학술지
Hanyang Medical Reviews
;
: 215-221, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-29871
ABSTRACT
The direct reprogramming of a terminally differentiated cell into another lineage using defined combinations of factors has fundamentally changed traditional concepts of the inalterability of differentiated cells. Many studies have achieved direct conversion into various cell types in recent years, and this strategy is considered to be a promising approach for inducing functional cells. Here, we review work on direct reprogramming, from the early pioneering studies to the most recent, including the discovery of novel reprogramming factors, molecular mechanisms, and strategies. We also discuss the applications of direct reprogramming and the perspectives and challenges of this novel technology.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Factores de Transcripción
/
Diferenciación Celular
/
Medicina Regenerativa
Idioma:
Inglés
Revista:
Hanyang Medical Reviews
Año:
2015
Tipo del documento:
Artículo
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