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The clinical evaluation of patients with pituitary adenomas undergone transsphenoidal microsurgery / 中华外科杂志
Chinese Journal of Surgery ; (12): 610-613, 2003.
Artículo en Chino | WPRIM | ID: wpr-299976
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the overall effect of transsphenoidal microsurgery for pituitary adenomas in recent 5 years and to discuss the surgical technique, application of new technology and postoperative follow-up results.</p><p><b>METHODS</b>The clinical presentation, image characteristics, endocrinal findings, pathological types, tumor removal percentage, postoperative complication and follow-up of 1 462 patients with pituitary adenomas who underwent the transsphenoidal microsurgery from 1997 to 2002 were analysed retrospectively.</p><p><b>RESULTS</b>Total rate of tumor removal for the patients achieved 97.0% in the patients with Hardy I adenomas, 95.2% with Hardy II, 90.5% with Hardy III, and 47.4% with Hardy IV respectively. A significant postoperative improvement both in clinical symptoms and endocrinal parameters was achieved. The tumor recurrence rate was 0.3%.</p><p><b>CONCLUSIONS</b>With the improvement of microsurgical technique and application of novel technology, the indication of transsphenoidal microsurgery for pituitary adenomas was increasingly extended. Endoscope and(/or) neuronavigation-assisted microsurgery via transsphenoidal approach should be of the first choice for the treatment of pituitary adenomas. The routine postoperative radiotherapy is not required for patients with total tumor removal.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neoplasias Hipofisarias / Seno Esfenoidal / Cirugía General / Adenoma / Estudios Retrospectivos / Estudios de Seguimiento / Resultado del Tratamiento / Procedimientos Neuroquirúrgicos / Métodos / Microcirugia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Surgery Año: 2003 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neoplasias Hipofisarias / Seno Esfenoidal / Cirugía General / Adenoma / Estudios Retrospectivos / Estudios de Seguimiento / Resultado del Tratamiento / Procedimientos Neuroquirúrgicos / Métodos / Microcirugia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Surgery Año: 2003 Tipo del documento: Artículo