Clinical analysis of combined resection for T4 gastric cancer: report of 69 cases / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the effect of combined resection for the treatment of T(4) gastric cancer and to refine the indication for en bloc dissection.</p><p><b>METHODS</b>Clinical data of 69 cases receiving combined resection were analyzed retrospectively, and compared with those of 45 cases undergoing palliative gastrectomy.</p><p><b>RESULTS</b>Of 69 cases, 54 patients underwent curative combined resection, 15 patients underwent palliative combined resection, including 24 with transverse colectomy, 22 with pancreatico-splenectomy, 8 with left lateral lobectomy of liver, 6 with pancreatico-splenectomy and transverse colectomy, 5 with pancreaticoduodenectomy, 2 with cholecystectomy, 1 with splenectomy, 1 with phrenectomy. The total rate of lymph node metastasis was 88.4%; the operative mortality rate was 4.3%; the morbidity rate was 14.5%. The postoperatively 1-, 3-, 5-year survival rates of CR group and NCR group were 66.9%, 39.1%, 26.8% and 33.4%, 7.4%, 0% respectively (P < 0.01). The five year survival rate of curative resection group was 34.1%.</p><p><b>CONCLUSIONS</b>An en bloc combined resection can cure some T(4) patients, and improve the five-year survival rate.</p>