Association of estrogen receptor gene polymorphisms and primary trigeminal neuralgia / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 495-497, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-300261
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the association of estrogen receptor (ER) gene polymorphism and primary trigeminal neuralgia.</p><p><b>METHODS</b>By polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), ER gene polymorphism was analyzed in 20 trigeminal neuralgia (TR) patients and 20 control individuals, and the distribution of ER genotype was compared in TR group and control group.</p><p><b>RESULTS</b>There was no significant difference in frequencies of allele and genotype in XbaI or PvuII polymorphism or XbaI with PvuII polymorphisms together between TR group and control group (P > 0.05). The genotypic distribution of Xx or PpXx in TR group was higher than control group, and it was contary to xx, ppxx or Ppxx in TR group and control group.</p><p><b>CONCLUSION</b>XbaI or PvuII polymorphism may be related to TR. Women with PpXx genotype may be a dangerous factor to primary trigeminal neuralgia.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polimorfismo Genético
/
Neuralgia del Trigémino
/
Receptores de Estrógenos
/
Reacción en Cadena de la Polimerasa
/
Genotipo
Límite:
Femenino
/
Humanos
Idioma:
Chino
Revista:
West China Journal of Stomatology
Año:
2005
Tipo del documento:
Artículo
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