Gastric Microbiota and Gastric Cancer
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
;
: 73-81, 2016.
Artículo
en Coreano
| WPRIM
| ID: wpr-30054
ABSTRACT
The stomach had been recognized as an organ where many bacteria cannot survive due to the presence of gastric acid. However, a number of bacteria have been detected after the discovery of Helicobacter pylori with recent advances in nucleotide sequencing techniques and bioinformatics. These include Proteobacteria, Firmicutes, Bacteroidetes, Actinobacteria and Fusobacteria. Several animal studies suggested that the imbalance of gastric microbiotas could be associated with the development of gastric cancer. Changes in the composition of the gastric microbiota may increase the production of N-nitroso compounds, which is known to be a carcinogen. Further studies on the actual function and proteomics of gastric microbiota could be beneficial for prevention, early diagnosis, and new treatment strategies of gastric cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Estómago
/
Neoplasias Gástricas
/
Bacterias
/
Helicobacter pylori
/
Actinobacteria
/
Biología Computacional
/
Proteobacteria
/
Proteómica
/
Bacteroidetes
/
Fusobacterias
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Límite:
Animales
Idioma:
Coreano
Revista:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Año:
2016
Tipo del documento:
Artículo
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