Research progress on the animal models and treatment strategies of diabetic foot ulcer / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 97-105, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-300817
ABSTRACT
The suitable experimental animal model is important in research of pathogenesis and therapeutic strategies of diabetic foot ulcer, and the murine model is the most commonly used one at present. It can be divided into two types the animal model simulating pathological conditions and the model simulating clinical symptoms. This article reviews the current research progress on the mechanisms of diabetic ulcer pathogenesis, and relevant treatment strategies, including the inhibition of matrix metalloproteinases (MMPs) expression, promotion of angiogenesis and anti-inflammatory therapy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Terapéutica
/
Pie Diabético
/
Neovascularización Fisiológica
/
Metaloproteinasas de la Matriz
/
Usos Terapéuticos
/
Modelos Animales de Enfermedad
/
Inhibidores de la Metaloproteinasa de la Matriz
/
Genética
/
Metabolismo
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2017
Tipo del documento:
Artículo
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