The impact of synapsins on synaptic plasticity and cognitive behaviors / 神经科学通报·英文版

ABSTRACT

Synapsins are a family of phosphoproteins specifically associated with the cytoplasmic surface of the synaptic vesicle membrane, appearing to regulate neurotransmitter release, the formation and maintenance of synaptic contacts. They could induce the change of the synaptic plasticity to regulate various adaptation reactions, and change the cognitive behaviors. So we presume that if some cognitive behaviors are damaged, synapsins would be changed as well. This gives us a new recognition of better diagnosis and therapy of cognitive disorder disease.