Prognostic differences among different age limits in Chinese elderly patients with non-Hodgkin's lymphoma / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To explore the feasible age limits in Chinese elderly patients with non-Hodgkin's lymphoma (NHL).</p><p><b>METHODS</b>The clinical data of 507 patients with NHL who were admitted to Peking Union Medical College Hospital (PUMCH) from January 1990 to December 2007 were retrospectively analyzed. They were further followed up by reviewing medical records or by phone. The deadline of follow-up was October 2008.</p><p><b>RESULTS</b>The 5-year/8-year overall survival (OS) rates were 64.6%/45.7%, 53.0%/ 44.1%, 32.8%/17.5%, 40.0%/22.8%, and 19.8%/0, respectively, in patients aged < 60 years, 60-64 years, 65-69 years, 70-74 years, and > or = 75 years. The OS rate was significantly different between patients aged > or = 75 years and other age groups, and between patients aged 65-70 years and patients younger than 60 years (P < 0.05). Only age, serum albumin, and hemoglobin affected the survival status in elderly NHL patients.</p><p><b>CONCLUSION</b>Sixty-five years can be regarded as the age limit in Chinese NHL patients.</p>