Morphology of nitric oxide synthase positive neurons in the cerebellar cortex of midanaphase human fetus / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 473-475, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-301669
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the growth and development of nitric oxide synthase (NOS)-positive neurons in the cerebellum of human fetus in the midanaphase.</p><p><b>METHOD</b>The positive expression of the NOS-positive neurons in the cerebellum of midanaphase human fetus was observed by immunohistochemistry.</p><p><b>RESULTS</b>By the sixth to seventh month of gestation, NOS-positive neurons were seen in the ependymal layer of the cerebellum. The nucleus was oval-shaped and the neurons had short and small processes. By the eighth to ninth month, NOS-positive neurons were found in the central layer of the cerebellum and the nucleus was round-, oval-, or fusiform-shaped; meanwhile, the neurons grew larger in size with richer cytoplast and heavier staining. The beaded nerve fibers reached the marginal layer and the layer became thickened on the tenth month, which generally was composed of 5 to 6 layers of NOS-positive neurons that were tightly aligned. Some NOS-positive neurons were in smaller size with the cell body and the nerve fibers grew well.</p><p><b>CONCLUSION</b>Nitric oxide generated by NOS of the NOS-positive neurons in the cerebellum plays an important role in the differentiation, proliferation, and migration of neurons and gliacytes.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Inmunohistoquímica
/
Corteza Cerebelosa
/
Óxido Nítrico Sintasa
/
Biología Celular
/
Óxido Nítrico Sintasa de Tipo I
/
Feto
/
Metabolismo
/
Fibras Nerviosas
/
Neuronas
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2009
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS