Diagnosis, treatment and prognosis of 34 patients with malignant primary intracranial teratoma / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 595-598, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-301927
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical characteristics, diagnosis and surgical treatment of malignant intracranial teratomas.</p><p><b>METHODS</b>Thirty-four patients with intracranial teratoma proved by histopathology were treated by operation. The growth pattern of this tumor, assessed by its clinical manifestations and neuroimaging together with surgical treatment and results were analyzed retrospectively.</p><p><b>RESULTS</b>Only 6 lesions had been correctly suspected as teratoma before surgery. Total removal was achieved in 14 patients with a operative mortality of 32.4%. The survival of 23 patients with lesions showing aggressive growth was significantly different from those without (P < 0.05). Nineteen of these patients did not survive beyond the sixth month after surgery.</p><p><b>CONCLUSION</b>Accurate preoperative diagnosis is difficult in malignant intracranial teratoma, especially for patients with the tumor in the sella region. The invasive biological behavior of the tumor is proved to be the main cause of surgery being dwarfed. Protection of the hypothalamus and brainstem, relief of hydrocephalus are the crucial points in surgical treatment. Comprehensive histopathologic examination combined with serum and CSF tumor marker detection is necessary for correct diagnosis and treatment.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Pronóstico
/
Cirugía General
/
Teratoma
/
Sangre
/
Neoplasias Encefálicas
/
Biomarcadores de Tumor
/
Líquido Cefalorraquídeo
/
Mortalidad
/
Diagnóstico
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Límite:
Adolescente
/
Adulto
/
Niño
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Oncology
Año:
2002
Tipo del documento:
Artículo
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