Your browser doesn't support javascript.
loading
Effect of umbilical cord MSC infusion on the pulmonary infection in haploidentical hematopoietic stem cell transplantation / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 1084-1088, 2014.
Artículo en Chino | WPRIM | ID: wpr-302343
ABSTRACT
This study was purposed to investigate the effect of umbilical cord mesenchymal cells (UC-MSC) infusion on the pulmonary infection in haploidentical hematopoietic stem cell transplantation (hi-HSCT). The infection of 83 patients underwent hi-HSCT was detected and analysed, among them 42 patients received haploidentical hi-HSCT, 41 received hi-HSCT combined with UC-MSC infusion. The results showed that 31 cases (73.81% ± 6.78%) were infected by cytomegalovirus and 21 cases in patients received hi-HSCT experienced pulmonary infections, including infections of fungal, virus, bacteria, tubercle bacillus, PCP and so on, the incidence rate was (50 ± 7.72)%; the infection of cytomegalovirus (CMV) was found in 31 cases, the incidence rate was (78.05 ± 6.46)%. In patients received hi-HSCT combined with UC-MSC, only 15 patients experienced pulmonary infection, the incidence rate was (36.59 ± 7.52)%, and the infection of cytomegalovirus (CMV) was observed in 32 patients, the incidence rate was (78.05 ± 6.46)%. There was no obvious statistical difference between two groups(P > 0.05). It is concluded that the UC-MSC infusion not increases the infection rate in hi-HSCT.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Trasplante Homólogo / Cordón Umbilical / Epidemiología / Resultado del Tratamiento / Infecciones por Citomegalovirus / Trasplante de Células Madre Hematopoyéticas / Acondicionamiento Pretrasplante / Biología Celular / Células Madre Mesenquimatosas / Enfermedades Pulmonares Límite: Adolescente / Adulto / Niño / Child, preschool / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Experimental Hematology Año: 2014 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Trasplante Homólogo / Cordón Umbilical / Epidemiología / Resultado del Tratamiento / Infecciones por Citomegalovirus / Trasplante de Células Madre Hematopoyéticas / Acondicionamiento Pretrasplante / Biología Celular / Células Madre Mesenquimatosas / Enfermedades Pulmonares Límite: Adolescente / Adulto / Niño / Child, preschool / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Experimental Hematology Año: 2014 Tipo del documento: Artículo