Structure identification of two new cerebrosides from Helicia nilagirica Beed / 药学学报

ABSTRACT

<p><b>AIM</b>To study the bioactive components from Helicia nilagirica.</p><p><b>METHODS</b>Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence.</p><p><b>RESULTS</b>Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1.</p><p><b>CONCLUSION</b>The two compounds are new cerebrosides.</p>