Steroids in traditional Chinese medicine: what is the evidence?
Singapore medical journal
;
: 115-120, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-304075
ABSTRACT
Local healthcare providers often question the possible steroidal activity of traditional Chinese medicine (TCM) herbs or herbal products and implicate them as a cause for adrenal insufficiency or Cushing's syndrome in patients with a history of TCM intake. We conducted a comprehensive database search for evidence of potential glucocorticoid, mineralocorticoid, androgenic or oestrogenic activity of herbs or herbal products. Overall, there are not many herbs whose steroidal activity is well established; among these, most cases were based on preclinical studies. Liquorice root may cause pseudoaldosteronism through interference with the steroidogenesis pathway. Although ginseng and cordyceps have some in vitro glucocorticoid activities, the corroborating clinical data is lacking. Deer musk and deer antler contain androgenic steroids, while epimedium has oestrogenic activity. On the other hand, adulteration of herbal products with exogenous glucocorticoids is a recurrent problem encountered locally in illegal products masquerading as TCM. Healthcare providers should stay vigilant and report any suspicion to the relevant authorities for further investigations.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Singapur
/
Esteroides
/
Extractos de Tejidos
/
Ciervos
/
Medicamentos Herbarios Chinos
/
Ácidos Grasos Monoinsaturados
/
Riesgo
/
Bases de Datos Factuales
/
Glycyrrhiza uralensis
/
Preparaciones de Plantas
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
Límite:
Animales
/
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Singapore medical journal
Año:
2017
Tipo del documento:
Artículo
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