The debate on treating subclinical hypothyroidism
Singapore medical journal
;
: 539-545, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-304115
ABSTRACT
Subclinical hypothyroidism (SCH) represents a mild or compensated form of primary hypothyroidism. The diagnosis of SCH is controversial, as its symptoms are non-specific and its biochemical diagnosis is arbitrary. The treatment of SCH was examined among non-pregnant adults, pregnant adults and children. In non-pregnant adults, treatment of SCH may prevent its progression to overt hypothyroidism, reduce the occurrence of coronary heart disease, and improve neuropsychiatric and musculoskeletal symptoms associated with hypothyroidism. These benefits are counteracted by cardiovascular, neuropsychiatric and musculoskeletal side effects. SCH is associated with adverse maternal and fetal outcomes that may improve with treatment. Treating SCH in children is safe and may improve growth. Importantly, the evidence in this field is largely from retrospective and prospective studies with design limitations, which precludes a conclusive recommendation for the treatment of SCH.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Complicaciones del Embarazo
/
Terapéutica
/
Sangre
/
Huesos
/
Biomarcadores
/
Estudios Prospectivos
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Resultado del Tratamiento
/
Progresión de la Enfermedad
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio observacional
/
Factores de riesgo
Límite:
Adolescente
/
Niño
/
Femenino
/
Humanos
/
Masculino
/
Embarazo
Idioma:
Inglés
Revista:
Singapore medical journal
Año:
2016
Tipo del documento:
Artículo
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