Effect of resection margin and tumor number on survival of patients with small liver cancer / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 928-931, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-304473
ABSTRACT
<p><b>OBJECTIVE</b>To explore the significance of resection margin and tumor number on survival of patients with small liver cancer after hepatectomy.</p><p><b>METHODS</b>We collected 219 cases with small liver cancer undergoing hepatectomy in Cancer Hospital, Chinese Academy of Medical Sciences between December 2003 to July 2013. The survival rates were compared by log-rank test between two resection margin groups (≥ 1 cm vs. <1 cm), different tumor number groups (single tumor vs. multiple tumors). We also performed a multifactor analysis by Cox model.</p><p><b>RESULTS</b>The 1-, 3-, 5- and 10- year overall survival rates were 95.9%, 85.3%, 67.8% and 53.3%, respectively, in all patients. The median survival time was 28 months in the group of <1 cm resection margin and 36 months in the group of ≥ 1 cm resection margin (P=0.249). The median survival time was 36 months in the group of single tumor and 26 months in the group of multiple tumors (P=0.448). The multifactor analysis also did not show significant effect of resection margin and tumor number on the patients' survival.</p><p><b>CONCLUSIONS</b>For small liver cancer, the resection margin of 1 cm might be advised. Increasing resection margin in further could probably not improve therapeutic effect. Standardized operation and combined treatment will decrease the negative influence of multiple tumors on overall survival.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Cirugía General
/
Factores de Tiempo
/
Tasa de Supervivencia
/
Mortalidad
/
Terapia Combinada
/
Hepatectomía
/
Neoplasias Hepáticas
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Oncology
Año:
2015
Tipo del documento:
Artículo
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