Genetic diversity of nucleocapsid genes of recent porcine epidemic diarrhea viruses isolated in Korea
Korean Journal of Veterinary Research
;
: 23-28, 2016.
Artículo
en Coreano
| WPRIM
| ID: wpr-30551
ABSTRACT
Porcine epidemic diarrhea virus (PEDV), a porcine enteropathogenic coronavirus, causes lethal watery diarrhea in piglets, resulting in large economic losses because of high mortality. In November 2013, PEDV reemerged in Korea, and these outbreaks have since continuously occurred. In the present study, we determined the full-length nucleocapsid (N) gene sequences of three Korean PEDV field isolates collected in 2014-2015. Sequence and phylogenetic analysis of N genes revealed that recent prevalent Korean PEDV isolates were very closely related to the US PEDV isolates in 2013. Interestingly, the phylogenetic tree based on the nucleotide sequencing of the PEDV N gene was similar to the tree topology of the PEDV complete genomes. Therefore, our data provide a better understanding of the genetic diversity and contribute to the accurate diagnosis and development of vaccines against PEDV.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Árboles
/
Variación Genética
/
Vacunas
/
Brotes de Enfermedades
/
Mortalidad
/
Genoma
/
Coronavirus
/
Nucleocápside
/
Diagnóstico
/
Diarrea
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Korean Journal of Veterinary Research
Año:
2016
Tipo del documento:
Artículo
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