Epidemiologic study and HLA analysis of highly exposed to HIV but persistently seronegative subjects (HEPS) in commercial blood donors in China / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 72-74, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-305521
ABSTRACT
<p><b>BACKGROUND</b>To investigate epidemiology and HLA typing of highly exposed to HIV but persistently seronegative subjects (HEPS) in commercial blood donors in China.</p><p><b>METHODS</b>This was a cohort study for epidemiologic characteristics of highly exposed but persistently seronegative subjects. PCR with sequence-specific primer and PCR-SSP for HLA typing were applied.</p><p><b>RESULTS</b>Eight HEPS were identified. Compared HLA typing with seropositive couple, high frequency of HLA-a24, HLA-B40 genotyping was observed.</p><p><b>CONCLUSION</b>Highly exposed to HIV but persistently seronegative subjects in commercial blood donors in China had high frequency of HLA-A24 and HLA-B40 genotype.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Virología
/
Sangre
/
Donantes de Sangre
/
Prueba de Histocompatibilidad
/
Anticuerpos Anti-VIH
/
Antígenos HLA-A
/
Infecciones por VIH
/
China
/
Reacción en Cadena de la Polimerasa
/
Epidemiología
Tipo de estudio:
Estudio de etiología
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Experimental and Clinical Virology
Año:
2006
Tipo del documento:
Artículo
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