Diagnosis and treatment of cytomegalovirus pneumonia after liver transplantation / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVES</b>To investigate the diagnosis and treatment of cytomegalovirus (CMV) pneumonia after liver transplantation.</p><p><b>METHODS</b>Five cases of CMV pneumonia after liver transplantation were analyzed retrospectively. CMV pneumonia was diagnosed according to its clinical manifestation, chest X-ray, and etiologic test. All 5 patients received comprehensive therapy based on anti-virus treatment and immunologic adjustment.</p><p><b>RESULTS</b>The clinical manifestation of CMV pneumonia after liver transplantation was nonspecific. Its main symptoms included fever, cough, dyspnea, tachycardia, fatigue, hypoxemia and neutropenia. The chest X-ray showed interstitial pneumonia. Sera CMV antigens or antibodies could be detected in the patients. Four patients were cured and 1 patient died.</p><p><b>CONCLUSIONS</b>The clinical manifestation of CMV pneumonia was nonspecific. CMV pneumonia could be diagnosed according to its manifestations, chest X-ray and etiologic test. The comprehensive therapy based on anti-virus treatment and immunologic adjustment was effective for the disease.</p>