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Experience of diagnosis and treatment of carcinoma arising from congenital biliary duct cyst / 中华外科杂志
Chinese Journal of Surgery ; (12): 839-841, 2005.
Artículo en Chino | WPRIM | ID: wpr-306201
ABSTRACT
<p><b>OBJECTIVE</b>To summarize the experience in diagnosis, prevention and treatment of carcinoma arising from congenital biliary duct cyst.</p><p><b>METHODS</b>The clinical and pathological data of 185 patients with congenital biliary duct cyst admitted to Chinese PLA General Hospital were analyzed retrospectively.</p><p><b>RESULTS</b>Among 185 patients, twenty-seven cases had carcinomas arising from congenital biliary duct cyst, and the frequency of malignant transformation was 14.6%, which closely related to the age (P < 0.001). The incidences of malignancy for different age groups were 0 for 0-9 age group, 5.1% for 0-19, 9.1% for 20-29, 16.2% for 30-39, 26.7% for 40-49, 33.3% for 50-59, and 50% for over 60, respectively. Six patients had the history of cyst-enterostomy. Abdominal pain, fever, jaundice and weight loss were the main clinical manifestations. Abdominal ultrasonography, CT, MRI or magnetic resonance cholangiopancreatography, MRCP and endoscopic retrograde choledochopancreatography (ERCP) were the main diagnostic methods. For twenty patients (74.1%), a definite diagnosis was made preoperatively, but it's hard to make an early diagnosis. Nine patients (33.3%) underwent curative resection.</p><p><b>CONCLUSIONS</b>Congenital biliary duct cyst is a premalignant lesion, and the incidence of carcinogenesis increases remarkably with age. The most effective method for prevention of carcinogenesis in choledochal cyst is complete excision of choledochal cyst during childhood, and the prognosis is poor for patients with biliary malignancy.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cirugía General / Tomografía Computarizada por Rayos X / Quiste del Colédoco / Estudios Retrospectivos / Colangiopancreatografia Retrógrada Endoscópica / Neoplasias del Conducto Colédoco / Diagnóstico Precoz / Pancreatocolangiografía por Resonancia Magnética / Diagnóstico Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio pronóstico / Estudio de tamizaje Límite: Adolescente / Anciano / Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino Idioma: Chino Revista: Chinese Journal of Surgery Año: 2005 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cirugía General / Tomografía Computarizada por Rayos X / Quiste del Colédoco / Estudios Retrospectivos / Colangiopancreatografia Retrógrada Endoscópica / Neoplasias del Conducto Colédoco / Diagnóstico Precoz / Pancreatocolangiografía por Resonancia Magnética / Diagnóstico Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio pronóstico / Estudio de tamizaje Límite: Adolescente / Anciano / Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino Idioma: Chino Revista: Chinese Journal of Surgery Año: 2005 Tipo del documento: Artículo