Biomechanical evaluation of immediate stability of biodegradable multi-amino acid copolymer/tri-calcium phosphate composite interbody Cages in a goat cervical spine model / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 63-66, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-306621
ABSTRACT
<p><b>UNLABELLED</b>A new kind of Interbody Cage made of multi-amino acid copolymer/tri-calcium phosphate (MAACP/TCP) composite was designed, and the purpose of this study was to evaluate immediate stability of MAACP/TCP Cage in a goat cervical spine model (C3-4). After the motion segment C3-4 was tested intact, 27 goat cervical spines were divided into three groups randomly. There were four groups group A. MAACP/TCP Cage group (n = 9), group B2 titanium Cage group (n = 9), group C2 autologous tricortical iliac crest bone group (n = 9) and group D intact group (n = 27). Different Cage groups were implanted after complete discectomy (C3-4) was performed. Then they were tested in flexion, extension, axial rotation, and lateral bending with a nondestructive stiffness method. The range of motion (ROM) and relative stiffness were calculated and compared between groups. In comparison to the intact motion segment, MAACP/TCP Cage showed a significantly (P < 0.05) lower ROM and a significantly (P < 0.05) higher relative stiffness in flexion and lateral bending. In comparison to the tricortical iliac crest bone graft, MAACP/TCP Cage showed a significantly (P < 0.05) lower ROM and a significantly (P < 0.05) higher relative stiffness in extension, flexion and lateral bending. There was no significant (P > 0.05) difference in the ROM and relative stiffness between MAACP/TCP Cage and titanium Cage in extension, flexion and lateral bending. In comparison to titanium Cage, MAACP/TCP Cage showed a significantly (P < 0.05) higher ROM and a significantly (P < 0.05) lower relative stiffness in rotation.</p><p><b>CONCLUSION</b>MAACP/TCP Cage can provide enough immediate stability for cervical interbody fusion in a goat cervical spine model.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polímeros
/
Fusión Vertebral
/
Cirugía General
/
Fenómenos Biomecánicos
/
Fosfatos de Calcio
/
Cabras
/
Vértebras Cervicales
/
Química
/
Implantes Experimentales
/
Implantes Absorbibles
Tipo de estudio:
Estudio diagnóstico
/
Estudios de evaluación
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2011
Tipo del documento:
Artículo
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