Effect of Bushen Yiqi Hexue recipe on endometrial P21 expression of embryo implantation dysfunctional mice / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2152-2155, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-307489
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Bushen Yiqi Hexue recipe on endometrial P21 and PCNA expression of embryo implantation dysfunctional mice.</p><p><b>METHOD</b>The expression of P21 protein was analyzed by means of immunoblot and immunohistochemical method. The expression of PCNA protein was analyzed by means of immunohistochemical method.</p><p><b>RESULT</b>The expression and disappearance of P21 and PCNA protein in endometrium of embryo implantation dysfunctional mice lagged behind in a temporal and cell specific manner. Bushenyiqihexue recipe could improve the expression of P21 and PCNA protein in a temporal and cell specific manner, and then improve the decidual reaction of endometrium of embryo implantation dysfunctional mice.</p><p><b>CONCLUSION</b>Improving the expression of P21 and PCNA protein in endometrium and eventually regulating endometrium decidual reaction is one of the mechanisms of improved embryo implantaion by Bushen Yiqi Hexue recipe.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Implantación del Embrión
/
Farmacología
/
Fisiología
/
Plantas Medicinales
/
Medicamentos Herbarios Chinos
/
Inmunohistoquímica
/
Immunoblotting
/
Química
/
Antígeno Nuclear de Célula en Proliferación
/
Combinación de Medicamentos
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2007
Tipo del documento:
Artículo
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