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Effect of Bushen Yiqi Hexue recipe on endometrial P21 expression of embryo implantation dysfunctional mice / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 2152-2155, 2007.
Artículo en Chino | WPRIM | ID: wpr-307489
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Bushen Yiqi Hexue recipe on endometrial P21 and PCNA expression of embryo implantation dysfunctional mice.</p><p><b>METHOD</b>The expression of P21 protein was analyzed by means of immunoblot and immunohistochemical method. The expression of PCNA protein was analyzed by means of immunohistochemical method.</p><p><b>RESULT</b>The expression and disappearance of P21 and PCNA protein in endometrium of embryo implantation dysfunctional mice lagged behind in a temporal and cell specific manner. Bushenyiqihexue recipe could improve the expression of P21 and PCNA protein in a temporal and cell specific manner, and then improve the decidual reaction of endometrium of embryo implantation dysfunctional mice.</p><p><b>CONCLUSION</b>Improving the expression of P21 and PCNA protein in endometrium and eventually regulating endometrium decidual reaction is one of the mechanisms of improved embryo implantaion by Bushen Yiqi Hexue recipe.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Implantación del Embrión / Farmacología / Fisiología / Plantas Medicinales / Medicamentos Herbarios Chinos / Inmunohistoquímica / Immunoblotting / Química / Antígeno Nuclear de Célula en Proliferación / Combinación de Medicamentos Límite: Animales Idioma: Chino Revista: China Journal of Chinese Materia Medica Año: 2007 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Implantación del Embrión / Farmacología / Fisiología / Plantas Medicinales / Medicamentos Herbarios Chinos / Inmunohistoquímica / Immunoblotting / Química / Antígeno Nuclear de Célula en Proliferación / Combinación de Medicamentos Límite: Animales Idioma: Chino Revista: China Journal of Chinese Materia Medica Año: 2007 Tipo del documento: Artículo