Studies on chemical constituents from root of Cynanchum atratum / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents from the roots and rhizome of Cynanchum atratum.</p><p><b>METHOD</b>The chemical constituents were isolated and repeatedly purified by silica gel chromatography and the structures were elucidated by the NMR spectra and physicochemical properties.</p><p><b>RESULT</b>Twelve compounds were obtained and nine of them were identified as 2, 4-dihyroxyacetophe none (1), 2, 6-dihyroxyacetophenone (2), 4-hydroxybenzenemethanol (3), benzoic acid (4), beta-amyrin acetate (5), palmitic acid (6), beta-sitosterol (7), beta-daucosterol (8), glaucogenin C-3-O-alpha-D-oleandropyranosyl-(1 --> 4)-beta-D-digitoxopyranosyl-(1 -->4)-alpha-D-oleandropyranoside (9).</p><p><b>CONCLUSION</b>Seven compounds were obtained from C. atratum for the first time.</p>