Evaluations of pre-thromboembolic state in patients undergoing total abdominal or laparoscopic hysterectomy / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the influences of total abdominal and laparoscopically hysterectomy on coagulation and fibrinolytic functions.</p><p><b>METHODS</b>Blood samples were taken from 20 patients without high-risk factor of thrombosis before and after total abdominal and laparoscopically hysterectomy. The values of PT, APTT, FG, D-Dimer and AT-III were measured.</p><p><b>RESULTS</b>The values of PT and AT-III significantly decreased while D-Dimer significantly increased after the operations. These changes were more obvious in patients undergoing abdominal hysterectomy. No significant changes in APTT or FG were noted after hysterectomy.</p><p><b>CONCLUSIONS</b>Patients undergoing hysterectomy are at risk of developing thromboembolism, but the laparoscopic approach can significantly lower this risk as compared with abdominal hysterectomy.</p>