Application of subclinical doses of pentazocine and propofol in painless vaginal egg retrieval / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To assess the feasibility of using subclinical doses of pentazocine in painless egg retrieval.</p><p><b>METHODS</b>Eighty-one patients undergoing painless egg retrieval were randomized into the observation group and the control group to receive 0.4 mg/kg pentazocine with 1.5 mg/kg propofol and 0.5 mg/kg pentazocine with 1.5 mg/kg propofol, respectively. The mean arterial pressure (MAP), heart rate (HR), SPO(2), respiratory rate (RR), unconsciousness time, awake time, hospital stay, complications, consciousness during the operation and adverse effects were compared between the two groups.</p><p><b>RESULTS</b>The two groups showed no significant differences in the analgesic effect, dosage of propofol, adverse effects, unconsciousness time, awake time, or hospital stay. But compared with the control group, the observation group showed greater intraoperative consciousness but with more stable respiration.</p><p><b>CONCLUSION</b>Subclinical doses of pentazocine can be used in the painless egg retrieval, but the dose of propofol should be increased to reduce the body activity during the operation.</p>