Allotransplantation of Leydig cells increases serum testosterone in rats / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the changes of serum testosterone after allotransplantation of Leydig cells in rats.</p><p><b>METHODS</b>Leydig cells were isolated from the testes of SD rats with the Percoll technique and serum testosterone of the receptors was determined once a month for 3 successive times.</p><p><b>RESULTS</b>After allotransplantation of Leydig cells, the serum testosterone level of the receptors increased gradually, significantly higher at 3 months than that of the normal rats younger than 2 months old.</p><p><b>CONCLUSION</b>Allotransplantation of Leydig cells has a promising application value in the treatment of male primary hypogonadism.</p>